Associate Professor Dana Stanley Agriculture, Science and the Environment
Agriculture, Science & the Environment / School of Health, Medical and Applied Sciences

Assoc Professor - Molecular Microbiology

Contact Details

Email: d.stanley@cqu.edu.au

Phone: (07) 4923 2079 - Ext: 52079

Office Location

Room 1.21

CQIRP

Ibis Avenue

About Me

Dr Stanley is one of Australia’s highest contributors to the field of poultry intestinal microbiota. Using sequencing technology and 16S rRNA gene to study microbial diversity is a relatively new approach that requires substantial knowledge of microbiology, molecular biology and bioinformatics.

Dr Stanley’s research on intestinal microbiota in health and disease focuses on the role of microbiota in poultry and other agricultural animals, as well as rodent models of human disease. She reported a relationship between intestinal bacteria and the ability of agricultural animals to retain energy from feed as well as the identification of phylotypes responsible for improved weight gain per unit of feed. She is currently developing probiotics with enhanced epigenetic effects to be used in agricultural breeding stock. Complementary to the role of microbiota in health, she is investigating the role of microbiota in disease prevention. Necrotic enteritis (NE) cost the international agricultural industry over $2 billion annually. Although it is widely accepted that Clostridium perfringens is the cause of NE, she proposed in her recent work that NE is considerably more complex than previously realised. She published on NE in 3 manuscripts, noting that 1) Induction of clinical symptoms requires the abundant intestinal bacteria, Weisella confusa, to be removed. She hypothesised that W. confusa, producer of gut epithelium protective mucous, prevents C. perfringens attaching to mucosa. 2) Although C. perfringens numbers increased in sick birds, the other unknown and unclassified order of Mollicutes, also involved in the onset of irritable bowel syndrome, increased much more than C. perfringens. 3) Virulent strain of C. perfringens administered in high doses during an experimental challenge is not capable of establishing itself in healthy birds but only in immuno-compromised hosts. 4) Well-known immunomodulating segmented filamentous bacteria (SFB) play a key role in preventing expansion of C. perfringens.

Additionally, Dr Stanley is a dedicated researcher is the area of poultry gut health and is one of the most published researchers at an international level, in the area of poultry gut heath and the role of optimal intestinal bacterial community in bird performance. Dr Stanley is currently investigating the nanoparticle based delivery of essential minerals and their ability to be used to deliver other treatments, such as antimicrobials and next generation probiotic development as a part of DECRA fellowship project. Dr Stanley is proactive and strongly associated with poultry industry collaborating with major poultry industry producers as evident from the current proposal.

Dana Stanley’s intestinal microbiota agricultural and veterinary research is complemented with human health studies. She established a reputation as a researcher in intestinal microbiota through long-term investigations in human health that resulted in high impact publications. She investigated how metabolic products from microbial fermentation of dietary fibre through metabolite-sensing receptors GPR43 and GPR109A prevent colitis (Nature Communications, 2015, 91 GS citations). Similarly, in another project she co-investigated the mechanisms behind microbiota-induced epigenetic effects in regulating the development of allergic airways disease (Nature Communications, 2015, 59 GS citations). Lastly her most recent manuscript (as a first author) was published in Nature Medicine (impact factor 33) reporting a microbiota role in post stroke mortality. This manuscript is considered game changing in our understanding of stroke mortality. It reveals that stroke event causes massive shock to immune and epithelial signalling system which results in compromised intestinal epithelial integrity and subsequent translocation of intestinal bacteria from the gut into the blood and organs. Gut permeability was highest at 3 hours post stroke, after which time epithelial integrity gets restored, however, a number of species comprising major lung pathogens already reached the lung at this stage and the unusual pneumonia, caused by dozens of different pathogens mounts antibiotic resistant lung infection that cannot be treated with antibiotics. Commonly administered antibiotics cannot cover the whole range of pathogens translocated to the lung. This manuscript received high media attention and was featured in Herald Sun, Morning Bulletin, Daily Telegraph Australia, Brisbane Courier-Mail and a number of radio interviews and it is of high clinical relevance.

Dana’s most recent publication, in Nature Immunology (impact 22), identifies the role of short chain fatty acids in the onset of type 1 diabetes (T1D). The modification of food to allow high concentrations of butyrate and/or acetate in the colon resulted in high level of protection from T1D, while combination of both high acetate and high butyrate provided total protection from T1D in NOD mouse T1D model. The fecal transplant from high acetate protected mice was able to confer protection in germ free recipients fed normal standard chow. Acetate was conferring protection via B-cell and butyrate via T-cell modifications.

In addition to the above high quality publications, Dr Stanley has been running clinical trials with the Clinical Research Institute as the lead investigator exploring the role of microbiota in cancer and removal of diabetes in post bariatric surgery, with first, high quality research outputs expected to be published in 2017.

Recently Dana was awarded ARC DECRA fellowship (started in 2016). Immediately after DECRA was announced her previous massive teaching load was almost completely removed; she has been since fully dedicated to research. DECRA-instigated teaching relief resulted in more than tripled research outputs in 2016: Dana submitted 17 manuscripts in 2016, 9 manuscripts were published in 2016 and another 5 already accepted/ published in early 2017 with others remaining under review. The significance of DECRA award for Dana’s career is becoming more evident comparing 2016 teaching-free research outputs with 2015 when she published 3 manuscripts. Dr Stanley’s work in intestinal health and microbiota is steadily growing in citations with annual citation number from 2014-2016 (GS) going from 91, 145 to 297 citations in 2016.

Dana has brought multiple grants from Poultry CRC and 2015 ARC DECRA fellowship. Total value of the grants DS is named as CI on is $833,824, out of that $663,824 as CIA.

In 7 years post PhD, Dana Stanley published 41 manuscripts, (32 journal manuscripts and 8 conference proceedings) with multiple Nature journals publications, 745 citations and H index 13 by Google Scholar, and Scopus 492 citations and H index 12. Level C academic, 7 yeast post PhD, ARC fellow, NHMRC panel reviewer.

Background

Gene expression

Metagenomics

Metabolimics

Microbiology

Intestinal microbiota

Probiotic development


Universities Studied At
Victoria University, Melbourne
Universities Worked At
CSIRO

Victoria University, Melbourne

Central Queensland University, Rockhampton

Poster Papers/ Published Research Summaries

1. Prasai, T. P., Walsh, K. B., Bhattarai, S. P., Midmore D. J., Van T. T., Moore R. J. and Stanley, D. Zeolite food supplementation reduces abundance of enterobacteria. Microbiological Research 195: 24-30. (2017).

2. Mariño, E., Richards, J., McLeod, K., Stanley, D., Yap, Y.E., Knight, J., McKenzie, C., Kranich, J., Oliveira, A., Rossello, F., Krishnamurthy, B., Nefzger, C., Macia, L., Thorburn, A., Baxter, A., Morahan, G., Wong, L., Polo, J.M., Moore, R.J., Lockett, T., Clarke, J., Topping, D., Harrison, L., and Mackay, C.R. (2017) "Gut microbial metabolites limit autoimmune T cell frequencies and protect against type 1 diabetes", Accepted in Nature Immunology, February 2017, in production, (2017).

3. Crisol-Martínez, E., Stanley, D., Geier, M.S, Hughes, R.J., and Moore, R.J. Understanding the mechanisms of zinc bacitracin and avilamycin on animal production: linking gut microbiota and growth performance in chickens. Accepted to Applied Microbiology and Biotechnology February 2017, in production, (2017).

4. Crisol-Martínez, E., Stanley, D., Geier, M.S., Hughes, R.J., and Moore, R.J. Sorghum and wheat differentially affect caecal microbiota and associated performance characteristics of meat chickens. Accepted to PeerJ February 2017, in production, (2017).

5. Batacan, R., Fenning, A., Dalbo, V.J., Scanlan, A.T., Duncan1,M., Moore, R.J., and Stanley, D. A gut reaction: The combined influence of exercise and diet on gastrointestinal microbiota in rats. Accepted in Journal of Applied Microbiology February 2017; in production (2017)

6. *Stanley, D., L. J. Mason, K. E. Mackin, Y. N. Srikhanta, D. Lyras, M. D. Prakash, K. Nurgali, A. Venegas, M. D. Hill, R. J. Moore and C. H. Wong. Translocation and dissemination of commensal bacteria in post-stroke infection. Nature Medicine 22(11): 1277-1284 (2016).

7. *Stanley D., Hughes R.J., Geier M.S., and Moore R.J. Bacteria within the gastrointestinal tract microbiota correlated with improved growth and feed conversion: Challenges presented for the identification of performance enhancing probiotic bacteria Frontiers in Microbiology 7(187) (2016).

8. *Wilkinson N., Hughes R.J., Aspden W.J., Chapman J., Moore R.J and Stanley D. The gastrointestinal tract microbiota of the Japanese quail, Coturnix japonica. Applied Microbiology and Biotechnology 15:51 1/13 1:9 (2016).

9. *Crisol-Martinez, E., Moreno-Moyano, L. T., Wilkinson, N., Prasai, T., Brown, P. H., Moore, R. J. and Stanley, D. A low dose of an organophosphate insecticide causes dysbiosis and sex-dependent responses in the intestinal microbiota of the Japanese quail (Coturnix japonica). PeerJ 4: e2002 (2016)

10. Crisol-Martinez, E., Moreno-Moyano, L. T., Wormington, K. R., Brown P. H., and Stanley D. Using Next-Generation Sequencing to Contrast the Diet and Explore Pest-Reduction Services of Sympatric Bird Species in Macadamia Orchards in Australia. PLoS One 11(3): e0150159 (2016).

11. Gangadoo, S., Stanley, D., Hughes, B., Moore R. J. and Chapman J. (2016). Nanoparticles in feed: progress and prospects in poultry research. (2016) Trends in Food Science & Technology 58: 115-126.

12. Moore, R. J. and Stanley, D. Experimental design considerations in microbiota/inflammation studies. Clinical and Translational Immunology 5 (7), e92 (2016).

13. *Prasai, T. P., Walsh, K. B., Bhattarai, S. P., Midmore, D. J., Van, T. T., Moore, R. J. and Stanley, D. Biochar, Bentonite and Zeolite Supplemented Feeding of Layer Chickens Alters Intestinal Microbiota and Reduces Campylobacter Load. PLoS One 11(4): e0154061. (2016).

14. Reynolds, A. C., Paterson, J. L., Ferguson, S. A., Stanley, D., Wright, D., K. P., Jr. and Dawson D. The shift work and health research agenda: Considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease. Sleep Medicine Reviews. DOI: 10.1016/j.smrv.2016.06.009 (2016).

15. * Thorburn, A.N., McKenzie, C.I., Shen, S., Stanley, D., Macia, L., Mason, L.J., Roberts, L.K., Wong, C.H.Y., Shim, R., Robert, R., Chevalier, N., Tan, J.K., Mariño, E., Moore, R.J., Wong, L., McConville, M.J., Tull, D.L., Wood, L.G., Murphy, V.A., Mattes, J., Gibson, P.R. & Mackay, C.R. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nature Communications -6:7320 (2015).

16. *Macia L., Vieira1 A.T., Tan .J., Stanley D., Canesso M.C.C., Luong S., Maruya M., Hijikata A., Binge L., Thorburn A., Maslowski K., Chevallier N., Mariño E., Robert R., Offermanns S., Teixeira M., da Silva Barcelos B., Moore R., Fagarasan S. and Mackay C.R. Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome Nature Communicatios 6:6734 (2015).

17. *Stanley D., Geier M.S., Hughes R.J., and Moore R.J. Comparison of fecal and cecal microbiotas reveals qualitative similarities but quantitative differences BMC Microbiology 15:51 (2015).

18. *Stanley D., Wu S., Rodgers N., Swick R.A., and Moore R.J. Differential responses of cecal microbiota to fishmeal, Eimeria and Clostridium perfringens in a necrotic enteritis challenge model in chickens. Plos One, 9, 8, e104739 (2014).

19. *Wu, S.B*., Stanley, D., Rodgers, N., Swick, R.A. & Moore, R.J. Two necrotic enteritis predisposing factors, dietary fishmeal and Eimeria infection, induce large changes in the caecal microbiota of broiler chickens. Veterinary Microbiology 169, 188-197 (2014).

20. *Stanley, D., Hughes, R.J. & Moore, R.J. Microbiota of the chicken gastrointestinal tract: Influence on health, productivity and disease. Applied Microbiology and Biotechnology 98(10):4301-10. (2014).

21. *Stanley, D., Watson-Haigh, N.S., Cowled, C.J. and Moore, R.J. Genetic architecture of gene expression in the chicken. BMC Genomics 14, 13 (2013).

22. *Stanley, D., Geier, M.S., Hughes, R.J., Denman, S.E. and Moore, R.J. Highly variable microbiota development in the chicken gastrointestinal tract. PLoS One 8, e84290 (2013).

23. *Stanley, D., Denman S.E., Hughes R.J., Geier M.S., Crowley T.M., Chen H., Haring V.R., and Moore R.J. Identification of chicken intestinal microbiota correlated with the efficiency of energy extraction from feed. Veterinary Microbiology 164, 85-92 (2013).

24. Gillespie, M.J., Crowley T.M., Haring V.R., Wilson S., Harper J.A., Payne J.S., Stanley D., Green D., Monaghan P., Donald J., Nicholas K.R. and Moore R.J. Transcriptome analysis of pigeon milk production - role of cornification and triglyceride synthesis genes. BMC Genomics 14, 169 (2013).

25. *Konsak, B.M., Stanley, D., Haring V.R., Geier M.S., Hughes R.J., Howarth G.S., Crowley T.M., and Moore R.J. et al. Gene expression patterns and microbiota correlated with differences in energy utilization in chickens. Animal Production Science 53, 12:19 (2013).

26. *Stanley, D., Keyburn, A.L., Denman, S.E. & Moore, R.J. Changes in the caecal microflora of chickens following Clostridium perfringens challenge to induce necrotic enteritis. Veterinary Microbiology 159, 155-162 (2012).

27. *Stanley, D., Denman S.E., Hughes R.J., Geier M.S., Crowley T.M., Chen. H., Haring V.R., and Moore R.J. Intestinal microbiota associated with differential feed conversion efficiency in chickens. Applied Microbiology and Biotechnology 96, 1361-1369 (2012).

28. *Gillespie, M.J., Stanley, D., Chen, H., Donald, J.A., Nicholas, K.R., Moore, R.J., and Crowley, T.M. Functional similarities between pigeon 'milk' and mammalian milk: induction of immune gene expression and modification of the microbiota. PLoS One 7, e48363 (2012).

29. *Stanley, D., Fraser, S., Stanley, G.A. & Chambers, P.J. Retrotransposon expression in ethanol-stressed Saccharomyces cerevisiae. Applied Microbiology and Biotechnology 87, 1447-1454 (2010).

30. *Stanley, D., Fraser, S., Chambers, P.J., Rogers, P. & Stanley, G.A. Generation and characterisation of stable ethanol-tolerant mutants of Saccharomyces cerevisiae. Journal of Industrial Microbiology and Biotechnology 37, 139-149 (2010).

31. *Stanley, D., Chambers, P.J., Stanley, G.A., Borneman, A. & Fraser, S. Transcriptional changes associated with ethanol tolerance in Saccharomyces cerevisiae. Applied Microbiology and Biotechnology 88, 231-239 (2010).

32. Stanley, D., Bandara, A., Fraser, S., Chambers, P.J. & Stanley, G.A. The ethanol stress response and ethanol tolerance of Saccharomyces cerevisiae. Journal of Applied Microbiology 109, 13-24 (2010).

Refereed Conferences

1. *Moore, R.J., Stanley, D., Konsak B.M., Haring V.R., Hughe s R.J., Geier M.S., Crowley T.M. Correlations between variable broiler performance, gene expression and microflora in the gut. Australian Poultry Science Symposium 22, 9-16 (2011).

2. *Stanley, D., Geier, M.S., Hughes, R.J. & Moore, R.J. The role of gastrointestinal tract microbiota in chicken productivity. Australian Poultry Science Symposium 23, 262-265 (2012).

3. Marino, E., Richards, J., McLeod, K., Yap, Y., Stanley, D., Mackay, C. Gut microbial metabolites regulate autoimmune T cell responses and protect against type 1 diabetes. European Journal Of Immunology, 46, 538-538 (2016).

4. McLeod, K., Stanley, D., Richards, J., Moore, R., Mackay, C., Marino, E. Changes of microbiota, and their metabolites, in in the development of T1D. European Journal Of Immunology, 46, 290-290 (2016).

5. Wong, C., Stanley, D., Mackin, K., Lyras, D., Prakash, M., Nurgali, K., Hill, M., Moore, R. Translocation and dissemination of commensal bacteria as a source of infection after stroke. European Journal Of Immunology, 46, 704-704 (2016).

6. Jordan, M.A., Gresle, M., Laverick, L., Stanley, D., Smith, L.,Spelman, T., Field, J., Johnson, L., Butzkueven, H., Baxter, A.G. Unravelling the multiple sclerosis complex disease trait through an immune transcriptional regulatory network approach. European Journal Of Immunology, 46, 292-293 (2016).

7. Jordan, M.A., Stanley, D., Moore, R., Baxter, A.G. The effect of microbiome/Toll-like receptor interactions on susceptibility to type 1 diabetes, European Journal Of Immunology, 46, 921-921 (2016).

8. Moore, R.J., Stanley, D., and Hughes, R.J. Microbiota studies in poultry: the black hole of complexity! Australian Poultry Science Symposium 28, 8-11 (2017).

Conference Presentations

1. Moore, R.J., Stanley, D., and Hughes, R.J. Microbiota studies in poultry: the black hole of complexity! Australian Poultry Science Symposium, APSS, Sydney, 2017.

2. Stanley, D., Translocation and dissemination of intestinal bacteria after stroke: the role of gut mucosal microbiota and Akkermansia muciniphila. Theo Murphy Australian Frontiers of Science. Invited presentation, Adelaide, Australia, 2016.

3. Stanley, D., Short Chain Fatty Acids can Remodel Intestinal Microbiota to Protect from Type 1 Diabetes, Invited speaker, 2nd Microbiome R&D and Business Collaboration Congress, Kuala Lumpur, 2016

4. Marino, E., Richards, J., McLeod, K., Yap, Y., Stanley, D., Mackay, C. 2016. Gut microbial metabolites regulate autoimmune T cell responses and protect against type 1 diabetes. Invited presentation, International Congress of Immunology Melbourne, Australia, 2016

5. McLeod, K., Stanley, D., Richards, J., Yap, Y., Moore, R., Mackay, C., Marino, E. Changes of microbiota, and their metabolites, in in the development of T1D. International Congress of Immunology, 2016, Melbourne, Australia, 2016.

6. Wong, C., Stanley, D., Mackin, K., Lyras, D., Prakash, M., Nurgali, K., Hill, M., Moore, R. 2016. Translocation and dissemination of commensal bacteria as a source of infection after stroke. International Congress of Immunology, 2016, Melbourne, Australia, 2016.

7. Jordan, M.A., Stanley, D., Moore, R., Crowley, B., Baxter, A.G. The effect of microbiome/Toll-like receptor interactions on susceptibility to type 1 diabetes, International Congress of Immunology, 2016, Melbourne, Australia, 2016.

8. Jordan, M.A., Gresle, M., Laverick, L., Stanley, D., Smith, L.,Spelman, T., Field, J., Johnson, L., Butzkueven, H., Baxter, A.G. Unravelling the multiple sclerosis complex disease trait through an immune transcriptional regulatory network approach, International Congress of Immunology, Melbourne, Australia, 2016.

9. Jordan M.A., Stanley D., Moore R.J., Hasnain S., McGuckin M., Butler T., Chowdhury S., Jose R., Biros E., Du Toit M., Law K., Socorro M.H., Crowley B., and Baxter A.G. The effect of microbiome/Toll-like receptor interactions on susceptibility to type 1 diabetes. The 13th International Congress of the Immunology of Diabetes Society, Lorne, Australia, 2013

10. Stanley D, Geier MS, Hughes RJ, Denman SE and Moore RJ. The gut microbiota’s role in chicken productivity. Australian Poultry Science Symposium, Sydney, Australia, 2012.

11. Moore RJ, Denman SE, Geier MS, and Stanley D. 2012. Intestinal microbiota associated with high feed conversion efficiency in chickens. International Symposium: Alternative to Antibiotics, Paris, France.

12. Moore RJ, Stanley D, Konsak BM, Haring VR, Hughes RJ, Geier MS and Crowley TM. Correlation between variable broiler performance and gene expression and microflora in the gut. Australian Poultry Science Symposium, Sydney, Australia 2011.

13. Stanley D., Fraser S., Chambers P.J., Rogers P.J., Stanley G.A. Generation and Characterisation of Ethanol-Tolerant Mutants. BioProcessing Network Conference. Abbosford. Victoria. 2008.

14. Stanley G., Bandara A., Stanley D., Fraser S., Chambres P. Yeast and Ethanol Stress. International Conference: National Center for Agricultural Utilisation Research, US Departement of Agriculture, Peoria USA. 2007.

15. Stanley D., Mohammed I., Fraser S., Chambers P.J., Rogers P.J., Stanley G.A. 2007. Ethanol Tolerant Mutants of Saccharomyces cerevisiae. Abstracts, Alcohol, Stress and Working with Yeasts. The XXIIIrd International Conference on Yeast Genetics and Molecular Biology Melbourne.

16. Stanley D., Fraser S., Chambers P.J., Rogers P.J., Stanley G.A. Using Ethanol Tolerant Mutants and Microarrays to Characterise the Molecular Response of Saccharomyces cerevisiae to Ethanol Stress. XXII. Abstracts, International Conference on Yeast Genetics and Molecular Biology. Bratislava, Slovak Republic. 2005.

17. Stanley D, Fraser S., Chambers PJ., Rogers P.J., Stanley G.A. Profiling Molecular Response of Saccharomyces cerevisiae to Ethanol Stress Using Ethanol Tolerant Mutants and Gene Arrays. Invited presentation, Eleventh International Congress on Yeasts, Rio De Janeiro, Brazil. 2004.

18. Stanley D., Fraser S., Chambers P.J., Rogers P.J., Stanley G.A. Adaptive Evolution in Generation of Ethanol Tolerant Mutants of Saccharomyces cerevisiae. Fermentation & Bioprocessing Interest Group (FBIG) conference, Melbourne. (Student best oral presentation award). 2004.

19. Stanley D, Fraser S, Chambers P.J., Rogers P.J., Stanley G.A. Ethanol Tolerant Mutants of Saccharomyces cerevisiae. Abstracts, Yeast: Product and Discovery, Barossa Valley, Australia, 2004.

BIOLOGICAL SCIENCES
Microbiology - Bacteriology
Gene expression Metagenomics Metabolimics Microbiology Intestinal microbiota Probiotic development
Journal article

Khalesi, S., Bellissimo, N., Vandelanotte, C., Williams, S., Stanley, D., & Irwin, C. (2019). A review of probiotic supplementation in healthy adults: helpful or hype?. European Journal of Clinical Nutrition, 73(1), 24-37. doi:10.1038/s41430-018-0135-9

Link to ACQUIRE

Stanley, D., Moore, R. J., & Wong, C. H. Y. (2018). An insight into intestinal mucosal microbiota disruption after stroke. Scientific Reports, 8, 1-12. doi:10.1038/s41598-017-18904-8

Link to ACQUIRE

Lacey, J. A., Stanley, D., Keyburn, A. L., Ford, M., Chen, H., Johanesen, P., . . . Moore, R. J. (2018). Clostridium perfringens-mediated necrotic enteritis is not influenced by the pre-existing microbiota but is promoted by large changes in the post-challenge microbiota. Veterinary Microbiology, 227, 119-126. doi:10.1016/j.vetmic.2018.10.022

Link to ACQUIRE

Wilkinson, N. E., Dinev, I., Aspden, W. J., Hughes, R. J., Christiansen, I., Chapman, J., . . . Stanley, D. (2018). Ultrastructure of the gastro intestinal tract of healthy Japanese quail (Coturnix japonica) using light and scanning electron microscopy. Animal Nutrition, 4(4), 378-387. doi:10.1016/j.aninu.2018.06.006

Link to ACQUIRE

Willson, N. -L., Nattrass, G. S., Hughes, R. J., Moore, R. J., Stanley, D., Hynd, P. I., & Forder, R. E. A. (2018). Correlations between intestinal innate immune genes and cecal microbiota highlight potential for probiotic development for immune modulation in poultry. Applied Microbiology and Biotechnology, 102(21), 9317-9329. doi:10.1007/s00253-018-9281-1

Link to ACQUIRE

Shen, S., Kumar, K. P., Stanley, D., Moore, R. J., Hao Van, T. T., Wen, S. W., . . . Wong, C. H. Y. (2018). Invariant natural killer T cells shape the gut microbiota and regulate neutrophil recruitment and function during intestinal inflammation. Frontiers in Immunology, 9(May 2018), 1-15. doi:10.3389/fimmu.2018.00999

Link to ACQUIRE

Baldwin, S., Hughes, R. J., Van, T. T. H., Moore, R. J., & Stanley, D. (2018). At-hatch administration of probiotic to chickens can introduce beneficial changes in gut microbiota. PLoS ONE, 13(3), 1-14. doi:10.1371/journal.pone.0194825

Link to ACQUIRE

Gangadoo, S., Dinev, I., Chapman, J., Hughes, R. J., Van, T. T. H., Moore, R. J., & Stanley, D. (2018). Selenium nanoparticles in poultry feed modify gut microbiota and increase abundance of Faecalibacterium prausnitzii. Applied Microbiology and Biotechnology, 102(3), 1455-1466. doi:10.1007/s00253-017-8688-4

Link to ACQUIRE

Jordan, M., Gresle, M. M., Laverick,, L., Stanley, D., Gemiarto, A., Smith, L. D., . . . Baxter, A. G. (2017). Dissecting the "killer module" and its role in Multiple Sclerosis. Multiple Sclerosis Journal, 23(13), N29-NP29. Retrieved from http://journals.sagepub.com/doi/full/10.1177/1352458517734699

Link to ACQUIRE

Abudabos, A. M., Al-Atiyat, R. M., Albatshan, H. A., Aljassim, R., Aljumaah, M. R., Alkhulaifi, M. M., & Stanley, D. M. (2017). Effects of concentration of corn distillers dried grains with solubles and enzyme supplementation on cecal microbiota and performance in broiler chickens. Applied Microbiology and Biotechnology, 101(18), 7017-7026. doi:10.1007/s00253-017-8448-5

Link to ACQUIRE

Abudabos, A. M., Al-Atiyat, R. M., Stanley, D., Aljassim, R., & Albatshan, H. A. (2017). The effect of corn distiller's dried grains with solubles (DDGS) fortified with enzyme on growth performance of broiler. Environmental Science and Pollution Research, 24(26), 21412-21421. doi:10.1007/s11356-017-9808-5

Link to ACQUIRE

Donaldson, E. E., Stanley, D., Hughes, R. J., & Moore, R. J. (2017). The time-course of broiler intestinal microbiota development after administration of cecal contents to incubating eggs. PeerJ, 5, 1-19. doi:10.7717/peerj.3587

Link to ACQUIRE

Batacan, R. B., Fenning, A. S., Dalbo, V. J., Scanlan, A. T., Duncan, M. J., Moore, R. J., & Stanley, D. (2017). A gut reaction: the combined influence of exercise and diet on gastrointestinal microbiota in rats. Journal of Applied Microbiology, 122(6), 1627-1638. doi:10.1111/jam.13442

Link to ACQUIRE

Crisol-Martínez, E., Stanley, D., Geier, M. S., Hughes, R. J., & Moore, R. J. (2017). Understanding the mechanisms of zinc bacitracin and avilamycin on animal production: Linking gut microbiota and growth performance in chickens. Applied Microbiology and Biotechnology, 101(11), 4547-4559. doi:10.1007/s00253-017-8193-9

Link to ACQUIRE

Crisol-Martínez, E., Stanley, D., Geier, M. S., Hughes, R. J., & Moore, R. J. (2017). Sorghum and wheat differentially affect caecal microbiota and associated performance characteristics of meat chickens. PeerJ, (3), 1-20. doi:10.7717/peerj.3071

Link to ACQUIRE

Mariño, E., Richards, J. L., McLeod, K. H., Stanley, D., Yap, Y. A., Knight, J., . . . Mackay, C. R. (2017). Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes. Nature Immunology, 18(5), 552-562. doi:10.1038/ni.3713

Link to ACQUIRE

Gangadoo, S., Stanley, D., Hughes, R. J., Moore, R. J., & Chapman, J. (2017). The synthesis and characterisation of highly stable and reproducible selenium nanoparticles. Inorganic and Nano-Metal Chemistry, 47(11), 1568-1576. doi:10.1080/24701556.2017.1357611

Link to ACQUIRE

Prasai, T. P., Walsh, K. B., Bhattarai, S. P., Midmore, D. J., Van, T. T. H., Moore, R. J., & Stanley, D. (2017). Zeolite food supplementation reduces abundance of enterobacteria. Microbiological Research, 195, 24-30. doi:10.1016/j.micres.2016.11.006

Link to ACQUIRE

Gangadoo, S., Stanley, D., Hughes, R. J., Moore, R. J., & Chapman, J. (2016). Nanoparticles in feed: Progress and prospects in poultry research. Trends in Food Science and Technology, 58, 115-126. doi:10.1016/j.tifs.2016.10.013

Link to ACQUIRE

Stanley, D., Mason, L. J., Mackin, K. E., Srikhanta, Y. N., Lyras, D., Prakash, M. D., . . . Wong, C. H. Y. (2016). Translocation and dissemination of commensal bacteria in post-stroke infection. Nature Medicine, 22(11), 1277-1284. doi:10.1038/nm.4194

Link to ACQUIRE

Moore, R. J., & Stanley, D. (2016). Experimental design considerations in microbiota/inflammation studies. Clinical and Translational Immunology, 5, 1-7. doi:10.1038/cti.2016.41

Link to ACQUIRE

Crisol-Martínez, E., Moreno-Moyano, L. T., Wilkinson, N., Prasai, T., Brown, P. H., Moore, R. J., & Stanley, D. (2016). A low dose of an organophosphate insecticide causes dysbiosis and sex-dependent responses in the intestinal microbiota of the Japanese quail (Coturnix japonica). PeerJ, 2016(5), 1-23. doi:10.7717/peerj.2002

Link to ACQUIRE

Wilkinson, N., Hughes, R. J., Aspden, W. J., Chapman, J., Moore, R. J., & Stanley, D. (2016). The gastrointestinal tract microbiota of the Japanese quail, Coturnix japonica. Applied Microbiology and Biotechnology, 100(9), 4201-4209. doi:10.1007/s00253-015-7280-z

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Prasai, T. P., Walsh, K., Bhattarai, S. P., Midmore, D. J., Van Thi, T. H., Moore, R. J., & Stanley, D. (2016). Biochar, bentonite and zeolite supplemented feeding of layer chickens alters intestinal microbiota and reduces campylobacter load. PLoS ONE, 11(4), 1-13. doi:10.1371/journal.pone.0154061

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Crisol-Martínez, E., Moreno-Moyano, L. T., Wormington, K. R., Brown, P. H., & Stanley, D. (2016). Using next-generation sequencing to contrast the diet and explore pest-reduction services of sympatric bird species in macadamia orchards in Australia. PLoS ONE, 11(3), 1-19. doi:10.1371/journal.pone.0150159

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Stanley, D., Hughes, R. J., Geier, M. S., & Moore, R. J. (2016). Bacteria within the gastrointestinal tract microbiota correlated with improved growth and feed conversion: Challenges presented for the identification of performance enhancing probiotic bacteria. Frontiers in Microbiology, 7, 1-13. doi:10.3389/fmicb.2016.00187

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Reynolds, A. C., Paterson, J. L., Ferguson, S. A., Stanley, D., Wright, K. P., & Dawson, D. (2017). The shift work and health research agenda: Considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease. Sleep Medicine Reviews, 34, 3-9. doi:10.1016/j.smrv.2016.06.009

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Stanley, D., Geier, M., Chen, H., Hughes, R., & Moore, R. (2015). Comparison of fecal and cecal microbiotas reveals qualitative similarities but quantitative differences. BMC microbiology., 15(1), 51-61. doi:10.1186/s12866-015-0388-6

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Thorburn, A., Shen, S., Stanley, D., Macia, L., Mason, L., Roberts, L., . . . Mackay, C. (2015). Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nature communications., 6, 1-13. doi:10.1038/ncomms8320

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Macia, L., Vieira, A., Leach, K., Stanley, D., Luong, S., Maruya, M., . . . Mackay, C. (2015). Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome. Nature communications., 6, 1-15. doi:10.1038/ncomms7734

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Gillespie, M. J., Crowley, T. M., Haring, V. R., Wilson, S. L., Harper, J. A., Payne, J. S., . . . Moore, R. J. (2014). Correction: Transcriptome analysis of pigeon milk production - role of cornification and triglyceride synthesis genes. BMC Genomics, 15(1), 185. doi:10.1186/1471-2164-15-185

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Stanley, D., Wu, S. B., Rodgers, N., Swick, R., & Moore, R. (2014). Differential responses of cecal microbiota to fishmeal, Eimeria and Clostridium perfringens in a necrotic enteritis challenge model in chickens. PLoS ONE., 9(8), 1-10. doi:10.1371/journal.pone.0104739

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Stanley, D., Hughes, R., & Moore, R. (2014). Microbiota of the chicken gastrointestinal tract : influence on health, productivity and disease. Applied microbiology and biotechnology., 98(10), 4301-4310. doi:10.1007/s00253-014-5646-2

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Wu, S. B., Stanley, D., Rodgers, N., Swick, R., & Moore, R. (2014). Two necrotic enteritis predisposing factors, dietary fishmeal and Eimeria infection, induce large changes in the caecal microbiota of broiler chickens. Veterinary microbiology., 169(3-4), 188-197. doi:10.1016/j.vetmic.2014.01.007

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Stanley, D., Watson-Haigh, N., Cowled, C., & Moore, R. (2013). Genetic architecture of gene expression in the chicken. BMC genomics., 14, 13-22. doi:10.1186/1471-2164-14-13

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Stanley, D., Geier, M., Hughes, R., Denman, S., & Moore, R. (2013). Highly variable microbiota development in the chicken gastrointestinal tract. PLoS ONE., 8(12), 1-7. doi:10.1371/journal.pone.0084290

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Stanley, D., Geier, M., Denman, S., Haring, V., Crowley, T., Hughes, R., & Moore, R. (2013). Identification of chicken intestinal microbiota correlated with the efficiency of energy extraction from feed. Veterinary microbiology., 164(1-2), 85-92. doi:10.1016/j.vetmic.2013.01.030

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Konsak, B., Stanley, D., Haring, V., Geier, M., Hughes, R., Howarth, G., . . . Moore, R. (2013). Identification of differential duodenal gene expression levels and microbiota abundance correlated with differences in energy utilisation in chickens. Animal production science., 53(12), 1269-1275. doi:10.1071/AN12426

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Gillespie, M. J., Stanley, D., Chen, H., Donald, J. A., Nicholas, K. R., Moore, R. J., & Crowley, T. M. (2012). Functional similarities between pigeon ‘milk’ and mammalian milk: Induction of immune gene expression and modification of the microbiota. PLoS ONE, 7(10), 1-10. doi:10.1371/journal.pone.0048363

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Stanley, D., Keyburn, A., Denman, S., & Moore, R. (2012). Changes in the caecal microflora of chickens following Clostridium perfringens challenge to induce necrotic enteritis. Veterinary microbiology., 159(1-2), 155-162. doi:10.1016/j.vetmic.2012.03.032

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Stanley, D., Denman, S., Hughes, R., Geier, M., Crowley, T., Chen, H., . . . Moore, R. (2012). Intestinal microbiota associated with differential feed conversion efficiency in chickens. Applied microbiology and biotechnology., 96(5), 1361-1369. doi:10.1007/s00253-011-3847-5

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Stanley, D., Fraser, S., Chambers, P., Rogers, P., & Stanley, G. (2010). Generation and characterisation of stable ethanol-tolerant mutants of Saccharomyces cerevisiae. Journal of industrial microbiology and biotechnology., 37, 139-149. doi:10.1007/s10295-009-0655-3

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Stanley, D., Fraser, S., Stanley, G., & Chambers, P. (2010). Retrotransposon expression in ethanol-stressed saccharomyces cerevisiae. Applied microbiology and biotechnology., 87(4), 1447-1454. doi:10.1007/s00253-010-2562-y

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Stanley, D., Bandara, A., Fraser, S., Chambers, P., & Stanley, G. (2010). The ethanol stress response and ethanol tolerance of Saccharomyces cerevisiae. Journal of applied microbiology., 109, 13-24. doi:10.1111/j.1365-2672.2009.04657.x

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Stanley, D., Chambers, P., Stanley, G., Borneman, A., & Fraser, S. (2010). Transcriptional changes associated with ethanol tolerance in saccharomyces cerevisiae. Applied microbiology and biotechnology., 88, 231-239. doi:10.1007/s00253-010-2760-7

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Higher Education
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BIOL12107 - Genomes, Genetics & Evolution
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